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Articles (116)
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Glucocorticoids increase the 1,25(OH)2D3receptor concentration in rat osteogenic sarcoma cells

Stavros C. Manolagas, Jean Abare, Leonard J. Deftos

Journal:

Calcified Tissue International

Année:

1984

Langue:

english

Fichier:

PDF, 394 KB

english, 1984

Comparison of 1,25-, 25-, and 24,25-hydroxylated vitamin D3binding in fetal rat calvariae and osteogenic sarcoma cells

Stavros C. Manolagas, Leonard J. Deftos

Journal:

Calcified Tissue International

Année:

1981

Langue:

english

Fichier:

PDF, 639 KB

english, 1981

Characterization of a human osteoblastic osteosarcoma cell line (SAOS-2) with high bone alkaline phosphatase activity

Elsa Murray, Diego Provvedini, Deborah Curran, Bayard Catherwood, Howard Sussman, Stavros Manolagas

Journal:

Journal of Bone and Mineral Research

Année:

1987

Langue:

english

Fichier:

PDF, 620 KB

english, 1987

Bone Marrow, Cytokines, and Bone Remodeling — Emerging Insights into the Pathophysiology of Osteoporosis

Epstein, Franklin H., Manolagas, Stavros C., Jilka, Robert L.

Journal:

Boston Medical and Surgical Journal

Année:

1995

Langue:

english

Fichier:

PDF, 191 KB

english, 1995

For whom the bell tolls: Distress signals from long-lived osteocytes and the pathogenesis of metabolic bone diseases

Manolagas, Stavros C., Parfitt, A. Michael

Journal:

Bone

Année:

2013

Langue:

english

Fichier:

PDF, 458 KB

english, 2013

The role of estrogen and androgen receptors in bone health and disease

Manolagas, Stavros C., O'Brien, Charles A., Almeida, Maria

Journal:

Nature Reviews Endocrinology (formerly Nature Clinical Practice Endocrinology & Metabolism)

Année:

2013

Langue:

english

Fichier:

PDF, 699 KB

english, 2013

Birth and Death of Bone Cells: Basic Regulatory Mechanisms and Implications for the Pathogenesis and Treatment of Osteoporosis 1

Manolagas, Stavros C.

Journal:

Endocrine Reviews

Année:

2000

Langue:

english

Fichier:

PDF, 2.28 MB

english, 2000

Estrogens and Androgens in Skeletal Physiology and Pathophysiology

Almeida, Maria, Laurent, Michaël R., Dubois, Vanessa, Claessens, Frank, O'Brien, Charles A., Bouillon, Roger, Vanderschueren, Dirk, Manolagas, Stavros C.

Journal:

Physiological Reviews

Année:

2017

Langue:

english

Fichier:

PDF, 2.91 MB

english, 2017

The quest for osteoporosis mechanisms and rational therapies: How far we've come, how much further we need to go

Manolagas, Stavros C.

Journal:

Journal of Bone and Mineral Research

Année:

2018

Langue:

english

Fichier:

PDF, 2.23 MB

english, 2018

Increased bone formation by prevention of osteoblast apoptosis with parathyroid hormone

Jilka, Robert L., Weinstein, Robert S., Bellido, Teresita, Roberson, Paula, Parfitt, A. Michael, Manolagas, Stavros C.

Journal:

Journal of Clinical Investigation

Année:

1999

Langue:

english

Fichier:

PDF, 255 KB

english, 1999

Inhibition of Osf2/Cbfa1 expression and terminal osteoblast differentiation by PPARγ2

Beata Lecka-Czernik, Igor Gubrij, Elena J. Moerman, Oumitana Kajkenova, David A. Lipschitz, Stavros C. Manolagas, Robert L. Jilka

Journal:

Journal of Cellular Biochemistry

Année:

1999

Langue:

english

Fichier:

PDF, 384 KB

english, 1999

Expression levels of gp130 in bone marrow stromal cells determine the magnitude of osteoclastogenic signals generated by IL-6-type cytokines

Charles A. O'Brien, Song-Chang Lin, Teresita Bellido, Stavros C. Manolagas

Journal:

Journal of Cellular Biochemistry

Année:

2000

Langue:

english

Fichier:

PDF, 151 KB

english, 2000

Continuous elevation of PTH increases the number of osteoblasts via both osteoclast-dependent and -independent mechanisms

Robert L Jilka, Charles A O'Brien, Shoshana M Bartell, Robert S Weinstein, Stavros C Manolagas

Journal:

Journal of Bone and Mineral Research

Année:

2010

Langue:

english

Fichier:

PDF, 1.21 MB

english, 2010

New insights into the cellular, biochemical, and molecular basis of postmenopausal and senile osteoporosis: Roles of IL-6 and gp130

Stavros C. Manolagas, Teresita Bellido, Robert L. Jilka

Journal:

International Journal of Immunopharmacology

Année:

1995

Langue:

english

Fichier:

PDF, 934 KB

english, 1995

Cytokines, hematopoiesis, osteoclastogenesis, and estrogens

Stavros C. Manolagas, Robert L. Jilka

Journal:

Calcified Tissue International

Année:

1992

Langue:

english

Fichier:

PDF, 471 KB

english, 1992

Endogenous glucocorticoids decrease skeletal angiogenesis, vascularity, hydration, and strength in aged mice

Robert S. Weinstein, Chao Wan, Qinglan Liu, Ying Wang, Maria Almeida, Charles A. O’Brien, Jeff Thostenson, Paula K. Roberson, Adele L. Boskey, Thomas L. Clemens, Stavros C. Manolagas

Journal:

Aging Cell

Année:

2010

Langue:

english

Fichier:

PDF, 1.01 MB

english, 2010

Kinase-mediated transcription, activators of nongenotropic estrogen-like signaling (ANGELS), and osteoporosis: A different perspective on the HRT dilemma

Manolagas, Stavros C., Kousteni, Stavroula, Chen, Jin-Ran, Schuller, Maria, Plotkin, Lilian, Bellido, Teresita

Journal:

Kidney International

Année:

2004

Langue:

english

Fichier:

PDF, 177 KB

english, 2004

The Role of IL-6 Type Cytokines and Their Receptors in Bonea

STAVROS C. MANOLAGAS

Journal:

Annals of the New York Academy of Sciences

Année:

1998

Fichier:

PDF, 956 KB

1998

Determinants of serum 1,25(OH)2D levels in renal disease

Cheung, Alfred K, Manolagas, Stavros C, Catherwood, Bayard D, Mosely, Coleman A, Mitas, John A, Blantz, Roland C, Deftos, Leonard J

Journal:

Kidney International

Année:

1983

Langue:

english

Fichier:

PDF, 532 KB

english, 1983

Osteocyte Apoptosis Is Induced by Weightlessness in Mice and Precedes Osteoclast Recruitment and Bone Loss

J Ignacio Aguirre, Lilian I Plotkin, Scott A Stewart, Robert S Weinstein, A Michael Parfitt, Stavros C Manolagas, Teresita Bellido

Journal:

Journal of Bone and Mineral Research

Année:

2006

Langue:

english

Fichier:

PDF, 2.20 MB

english, 2006

Perspective: Quantifying Osteoblast and Osteocyte Apoptosis: Challenges and Rewards

Robert L Jilka, Robert S Weinstein, A Michael Parfitt, Stavros C Manolagas

Journal:

Journal of Bone and Mineral Research

Année:

2007

Langue:

english

Fichier:

PDF, 933 KB

english, 2007

Extracellular Matrix Made by Bone Marrow Cells Facilitates Expansion of Marrow-Derived Mesenchymal Progenitor Cells and Prevents Their Differentiation Into Osteoblasts

Xiao-Dong Chen, Vladimir Dusevich, Jian Q Feng, Stavros C Manolagas, Robert L Jilka

Journal:

Journal of Bone and Mineral Research

Année:

2007

Langue:

english

Fichier:

PDF, 5.74 MB

english, 2007

Connexin 43 Is Required for the Anti-Apoptotic Effect of Bisphosphonates on Osteocytes and Osteoblasts In Vivo

Lilian I Plotkin, Virginia Lezcano, Jeff Thostenson, Robert S Weinstein, Stavros C Manolagas, Teresita Bellido

Journal:

Journal of Bone and Mineral Research

Année:

2008

Langue:

english

Fichier:

PDF, 2.55 MB

english, 2008

Estrogens attenuate oxidative stress and the differentiation and apoptosis of osteoblasts by DNA-binding-independent actions of the ERα

Maria Almeida, Marta Martin-Millan, Elena Ambrogini, Robert Bradsher III, Li Han, Xiao-Dong Chen, Paula K Roberson, Robert S Weinstein, Charles A O'Brien, Robert L Jilka, Stavros C Manolagas

Journal:

Journal of Bone and Mineral Research

Année:

2010

Langue:

english

Fichier:

PDF, 597 KB

english, 2010

Increased Adipogenesis and Myelopoiesis in the Bone Marrow of SAMP6, a Murine Model of Defective Osteoblastogenesis and Low Turnover Osteopenia

Oumitana Kajkenova, Beata Lecka-Czernik, Igor Gubrij, Simon P. Hauser, Kenshirou Takahashi, A. Michael Parfitt, Robert L. Jilka, Stavros C. Manolagas, David A. Lipschitz

Journal:

Journal of Bone and Mineral Research

Année:

1997

Langue:

english

Fichier:

PDF, 395 KB

english, 1997

Quantification of Vitamin D Receptor mRNA by Competitive Polymerase Chain Reaction in PBMC: Lack of Correspondence with Common Allelic Variants

Hanna Mocharla, Anthony W. Butch, Alex A. Pappas, James T. Flick, Robert S. Weinstein, Pietro De Togni, Robert L. Jilka, Paula K. Roberson, A. Michael Parfitt, Stavros C. Manolagas

Journal:

Journal of Bone and Mineral Research

Année:

1997

Langue:

english

Fichier:

PDF, 342 KB

english, 1997

Osteoblast Programmed Cell Death (Apoptosis): Modulation by Growth Factors and Cytokines

Robert L. Jilka, Robert S. Weinstein, Teresita Bellido, A. Michael Parfitt, Stavros C. Manolagas

Journal:

Journal of Bone and Mineral Research

Année:

1998

Langue:

english

Fichier:

PDF, 253 KB

english, 1998

New Developments in the Pathogenesis and Treatment of Steroid-Induced Osteoporosis

Stavros C. Manolagas, Robert S. Weinstein

Journal:

Journal of Bone and Mineral Research

Année:

1999

Langue:

english

Fichier:

PDF, 1.43 MB

english, 1999

Essential Requirement of BMPs-2/4 for Both Osteoblast and Osteoclast Formation in Murine Bone Marrow Cultures from Adult Mice: Antagonism by Noggin

Etsuko Abe, Matsuo Yamamoto, Yasuto Taguchi, Beata Lecka-Czernik, Charles A. O'Brien, Aris N. Economides, Neil Stahl, Robert L. Jilka, Stavros C. Manolagas

Journal:

Journal of Bone and Mineral Research

Année:

2000

Langue:

english

Fichier:

PDF, 1.66 MB

english, 2000

Chromosomal Mapping of Osteopenia-Associated Quantitative Trait Loci Using Closely Related Mouse Strains

Helen Beneš, Robert S. Weinstein, Wenhui Zheng, John J. Thaden, Robert L. Jilka, Stavros C. Manolagas, Robert J. Shmookler Reis

Journal:

Journal of Bone and Mineral Research

Année:

2000

Langue:

english

Fichier:

PDF, 169 KB

english, 2000

Corticosteroids and Fractures: A Close Encounter of the Third Cell Kind

Stavros C. Manolagas

Journal:

Journal of Bone and Mineral Research

Année:

2000

Langue:

english

Fichier:

PDF, 133 KB

english, 2000

1α,25-Dihydroxyvitamin D3 receptors in human thymic and tonsillar lymphocytes

Diego M. Provvedini, Christine M. Rulot, Robert E. Sobol, Constantine D. Tsoukas, Dr. Stavros C. Manolagas

Journal:

Journal of Bone and Mineral Research

Année:

1987

Langue:

english

Fichier:

PDF, 677 KB

english, 1987

Cytokine production and surface antigen expression by peripheral blood mononuclear cells in postmenopausal osteoporosis

Frank G. Hustmyer, Edwin Walker, Xiao-Peng Yu, Giuseppe Girasole, Yoshiyuki Sakagami, Munro Peacock, Stavros C. Manolagas

Journal:

Journal of Bone and Mineral Research

Année:

1993

Langue:

english

Fichier:

PDF, 762 KB

english, 1993

Reply

Stavros C. Manolagas, Giuseppe Girasole, Xiao-Peng Yu

Journal:

Journal of Bone and Mineral Research

Année:

1993

Langue:

english

Fichier:

PDF, 213 KB

english, 1993

Stimulation of interleukin-6 production by either calcitonin gene-related peptide or parathyroid hormone in two phenotypically distinct bone marrow-derived murine stromal cell lines

Y. Sakagami, G. Girasole, X.-P. Yu, H.S. Boswell, Stavros C. Manolagas

Journal:

Journal of Bone and Mineral Research

Année:

1993

Langue:

english

Fichier:

PDF, 508 KB

english, 1993

In vivo visualization of aging-associated gene transcription: evidence for free radical theory of aging

Jian Zhang, Jinlu Dai, Yi Lu, Zhi Yao, Charles A O'Brien, Jill M Murtha, Weici Qi, Daniel E Hall, Stavros C Manolagas, William B Ershler, Evan T Keller

Journal:

Experimental Gerontology

Année:

2004

Langue:

english

Fichier:

PDF, 440 KB

english, 2004

Corrigendum to “In vivo visualization of aging-associated gene transcription: evidence for free radical theory of aging” [Exp Gerontol 39 (2004) 239–247]

Jian Zhang, Jinlu Dai, Yi Lu, Zhi Yao, Charles A O'Brien, Jill M Murtha, Weici Qi, Daniel E Hall, Stavros C Manolagas, William B Ershler, Evan T Keller

Journal:

Experimental Gerontology

Année:

2004

Langue:

english

Fichier:

PDF, 42 KB

english, 2004

Breast Cancer Increases Osteoclastogenesis by Secreting M-CSF and Upregulating RANKL in Stromal Cells

Anne T. Mancino, V.Suzanne Klimberg, Matsuo Yamamoto, Stavros C. Manolagas, Etsuko Abe

Journal:

Journal of Surgical Research

Année:

2001

Langue:

english

Fichier:

PDF, 165 KB

english, 2001

Dissociation of the pro-apoptotic effects of bisphosphonates on osteoclasts from their anti-apoptotic effects on osteoblasts/osteocytes with novel analogs

Lilian I. Plotkin, Stavros C. Manolagas, Teresita Bellido

Journal:

Bone

Année:

2006

Langue:

english

Fichier:

PDF, 650 KB

english, 2006

A novel locus on the X chromosome regulates post-maturity bone density changes in mice

Dorota Szumska, Helen Beneš, Ping Kang, Robert S. Weinstein, Robert L. Jilka, Stavros C. Manolagas, Robert J. Shmookler Reis

Journal:

Bone

Année:

2007

Langue:

english

Fichier:

PDF, 937 KB

english, 2007

Intermittent PTH stimulates periosteal bone formation by actions on post-mitotic preosteoblasts

Robert L. Jilka, Charles A. O'Brien, A. Afshan Ali, Paula K. Roberson, Robert S. Weinstein, Stavros C. Manolagas

Journal:

Bone

Année:

2009

Langue:

english

Fichier:

PDF, 1.65 MB

english, 2009

FoxO-Mediated Defense against Oxidative Stress in Osteoblasts Is Indispensable for Skeletal Homeostasis in Mice

Elena Ambrogini, Maria Almeida, Marta Martin-Millan, Ji-Hye Paik, Ronald A. DePinho, Li Han, Joseph Goellner, Robert S. Weinstein, Robert L. Jilka, Charles A. O'Brien, Stavros C. Manolagas

Journal:

Cell Metabolism

Année:

2010

Langue:

english

Fichier:

PDF, 575 KB

english, 2010

What old means to bone

Stavros C. Manolagas, A. Michael Parfitt

Journal:

Trends in Endocrinology & Metabolism

Année:

2010

Langue:

english

Fichier:

PDF, 585 KB

english, 2010

Apoptosis and osteoporosis

Robert S. Weinstein, Stavros C. Manolagas

Journal:

The American Journal of Medicine

Année:

2000

Langue:

english

Fichier:

PDF, 1.15 MB

english, 2000

Parathyroid hormone and corticosteroid-induced osteoporosis

Stavros C Manolagas, Robert S Weinstein, Robert L Jilka, A Michael Parfitt

Journal:

The Lancet

Année:

1998

Langue:

english

Fichier:

PDF, 44 KB

english, 1998

Age-related bone loss: lessons from the osteoporotic SAMP6 mouse model

Robert L. Jilka, Robert J. Shmookler Reis, Stavros C. Manolagas

Journal:

International Congress Series

Année:

2004

Langue:

english

Fichier:

PDF, 254 KB

english, 2004

Studies of the internalization of vitamin D3 metabolites by cultured osteogenic sarcoma cells and their application to a non-chromatographic cytoreceptor assay for 1,25-dihydroxyvitamin D3

Stavros C. Manolagas, Leonard J. Deftos

Journal:

Biochemical and Biophysical Research Communications

Année:

1980

Langue:

english

Fichier:

PDF, 423 KB

english, 1980

MOLECULAR ACTION OF 1,25-DIHYDROXYVITAMIN D3: NEW CULTURED CELL MODELS

Mark R. Haussler, J. Wesley Pike, John S. Chandler, Stavros C. Manolagas, Leonard J. Deftos

Journal:

Annals of the New York Academy of Sciences

Année:

1981

Langue:

english

Fichier:

PDF, 874 KB

english, 1981

Giant Osteoclast Formation and Long-Term Oral Bisphosphonate Therapy

Weinstein, Robert S., Roberson, Paula K., Manolagas, Stavros C.

Journal:

Boston Medical and Surgical Journal

Année:

2009

Langue:

english

Fichier:

PDF, 677 KB

english, 2009

Interactions of 1,25-dihydroxyvitamin D3 and the immune system

Manolagas, Stavros C., Provvedini, Diego M., Tsoukas, Constantine D.

Journal:

Molecular and Cellular Endocrinology

Année:

1985

Langue:

english

Fichier:

PDF, 778 KB

english, 1985